https://www.science.org/doi/10.1126/sciadv.abl3522,
Leap Forward in Genetic Sequencing Will Lead to Improved Personalized Medicine and Understanding of Evolution
The most evolutionary refined process in biology is horrible.
And the brain is the newest and the least refined one, must be many orders of magnitude worse.
Make your conclusions.
The bacteria in question: Thermus aquaticus lives at temperatures above 131 °F, so it is clearly not using normal cellular chemistry.
https://en.wikipedia.org/wiki/DNA_replication
In general, DNA polymerases are highly accurate, with an intrinsic error rate of less than one mistake for every 10^7 nucleotides added.
The enzyme they are talking about was first discovered in that bacteria, but from my reading of the article, it was found to be pretty universal, that’s why they use it in PCR. Sorry if I got that wrong.
Yes, more accurate in higher organisms. My point was efficiency, not accuracy.
You are right, this issue seems be specific to Taq. Sorry I misread the paper.
So, it doesn’t support my point about the brain, but it has plenty of other support :).