Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learninghttps://pubmed.ncbi.nlm.nih.gov/40245144/
"we found that apical and basal dendrites of layer 2/3 (L2/3) pyramidal neurons showed distinct activity-dependent synaptic plasticity rules. Strengthening of apical and of basal synapses is predicted by local coactivity with nearby synapses and activity coincident with postsynaptic action potentials, respectively. Blocking postsynaptic spiking diminished basal synaptic potentiation without affecting apical plasticity. "