How many of those are pyramidal cells? How many inhibitory and which kinds? And how are these topologically arranged?
I used figures 8 and 9 of “Izhikevich & Edelman 2008 Large-scale model of mammalian thalamocortical systems (SI Appendix)” to configure the HTM-scheme untangling_sequences experiment (an extension of Numenta’s combined_sequences project). Their figure 9 table of neuron types and synaptic connectivity, assembled from multiple earlier studies, appears comprehensive but it seems to me that there could be a few arbitrary assumptions in the counts shown. I would be interested in any similar numerical analysis of cortical microcircuitry.
(untangling_sequences models L2/3 with the column pooler algorithm and L4 with apical tiebreak temporal memories; based on the above, it is typically configured to model 30 p2/3 pyramids and 30 L4 excitatory cells (10 each of ss4(L4), ss4(L2/3), p4) per minicolumn. So a run with 25 “cortical columns” of 100 minicolumns each is simulating 150k neurons (but typical training creates only about 80 synapses per cell))