TL;DR: In addition to spiking earlier, does a neuron in the predictive state burst fire upon receiving sensory input?
Input to the apical zone (feedback compartment) of a pyramidal neuron can cause a dendritic calcium spike, leading to burst firing in the neuron. As well, the apical zone can modulate somatic APs into bursts via BAC firing.
When I try to find info on whether basal NMDA spikes can modulate bursts, I read that:
however, a single NMDA spike cannot trigger a somatic action potential or can trigger only a single action potential
I can’t tell if the article is saying that NMDA spikes cannot cause bursting (without driving input), or if NMDA spikes are unable to modulate an somatic AP into burst firing (with driving input). I can’t find something definitively saying that basal NMDA spikes can modulate bursting.
HTM theory holds that an NMDA spike modulates a neuron by making it spike earlier, which is important to a WTA circuit. However, I was wondering if it is also the case that the depolarized somatic state from contextual input leads the neuron to burst fire, or if this is something that only the Feedback compartment is able to do with calcium spikes?