I have a question: does anybody know an open database, where information on the anatomy of the neocortex is collected?
Reason: I usually have troubles finding the right papers to do my research. It is usually very hard to find information to specific questions, e.g. you might want to check: what is the connection probability between the L5 thick tufted cells and L6 cortico-thalamic neurons? To which dendritic segments do they connect, how is this different across species, etc.
I think a lot of this information is out there, but hidden deep in some papers and not easily accessible. For me the hardest part is to find those papers and extract what they have to say on specific connections. Usually you have to check multiple papers to get a better overview.
I think a database collection with this information and referencing the original material could be beneficial to many people, and some of them could be willing to extend it, similar to Wikipedia.
However I do not know of such a project and wanted to ask if anybody does.
I can also see some troubles:
- how to structure it? Using tags like L5, L6a, thick-tufted, cortico-thalamic, etc.
- can this be integrated into existing projects, like Wikipedia?
Would be cool to hear your thoughts and doubts! And also how you usually do your research and how you test your hypothesis (to fit it to the data).